Discover the wonders of our immune system in this visualization of T cell maturation, capturing the transformation of T cells in the thymus (nest)! From their humble beginnings as immature T cells, they undergo a captivating maturation process.
In the Double-Positive (DP) stage (eggs in the nest), these budding T cells express both CD4 and CD8 co-receptors on their surface. This stage serves as a crucial checkpoint in their development, paving the way for their future roles.
They mature into CD4+ helper T cells or CD8+ cytotoxic T cells (birds). The molecule distinguishing the two is the Major Histocompatibility Complex (molecule in the birds).
CD4+ helper T cells act as conductors, orchestrating the immune response and assisting other immune cells. Meanwhile, CD8+ cytotoxic T cells eliminate infected or abnormal cells.
